Analytical Performance Validation of Next-Generation Sequencing Based Clinical Microbiology Assays Using a K-mer Analysis Workflow

Analytical Performance Validation of Next-Generation Sequencing Based Clinical Microbiology Assays Using a K-mer Analysis Workflow

Next-generation sequencing (NGS) enables clinical microbiology assays such as molecular typing of bacterial isolates which is now routinely applied for infection control and epidemiology. Additionally, feasibility for NGS-based identification of antimicrobial resistance (AMR) markers as well as gene...

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Bibliographic Details
Main Authors: Sarah Lepuschitz, Thomas Weinmaier, Katharina Mrazek, Stephan Beisken, Johannes Weinberger, Andreas E. Posch
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Microbiology
Subjects:
antimicrobial resistance
whole genome sequencing
human pathogens
workflow validation
k-mer analysis
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01883/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01883/full

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