Intermittent Hypoxia-Induced Activation of Endothelial Cells Is Mediated via Sympathetic Activation-Dependent Catecholamine Release

Intermittent Hypoxia-Induced Activation of Endothelial Cells Is Mediated via Sympathetic Activation-Dependent Catecholamine Release

Obstructive sleep apnea (OSA) is a common breathing disorder affecting a significant percentage of the adult population. OSA is an independent risk factor for cardiovascular disease (CVD); however, the underlying mechanisms are not completely understood. Since the severity of hypoxia correlates with...

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Bibliographic Details
Main Authors: Rengul Cetin-Atalay, Angelo Y. Meliton, David Wu, Parker S. Woods, Kaitlyn A. Sun, Ying-Jie Peng, Jayasri Nanduri, Xiaoyu Su, Yun Fang, Robert B. Hamanaka, Nanduri Prabhakar, Gökhan M. Mutlu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Physiology
Subjects:
obstructive sleep apnea
endothelial cell
epinephrine (adrenaline)
intermittent hypoxia
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.701995/full

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https://www.frontiersin.org/articles/10.3389/fphys.2021.701995/full

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