Receptor tyrosine kinase profiling of ischemic heart identifies ROR1 as a potential therapeutic target

Receptor tyrosine kinase profiling of ischemic heart identifies ROR1 as a potential therapeutic target

Abstract Background Receptor tyrosine kinases (RTK) are potential targets for the treatment of ischemic heart disease. The human RTK family consists of 55 members, most of which have not yet been characterized for expression or activity in the ischemic heart. Methods RTK gene expression was analyzed...

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Bibliographic Details
Main Authors: Juho Heliste, Anne Jokilammi, Ilkka Paatero, Deepankar Chakroborty, Christoffer Stark, Timo Savunen, Maria Laaksonen, Klaus Elenius
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Cardiovascular Disorders
Subjects:
Hypoxia
Ischemic cardiomyopathy
Myocardial ischemia
Myocardial infarction
Receptor tyrosine kinase
Online Access:http://link.springer.com/article/10.1186/s12872-018-0933-y

Internet

http://link.springer.com/article/10.1186/s12872-018-0933-y

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