Structural characterization of EGFR exon 19 deletion mutation using molecular dynamics simulation.

by Mahlet Z Tamirat, Marika Koivu, Klaus Elenius, Mark S Johnson
Published 2019-01-01

Combined genetic and chemical screens indicate protective potential for EGFR inhibition to cardiomyocytes under hypoxia

by Juho Heliste, Anne Jokilammi, Katri Vaparanta, Ilkka Paatero, Klaus Elenius
Published 2021-08-01

Structural Basis for the Functional Changes by EGFR Exon 20 Insertion Mutations

by Mahlet Z. Tamirat, Kari J. Kurppa, Klaus Elenius, Mark S. Johnson
Published 2021-03-01

Therapeutic Potential of Targeting the SUMO Pathway in Cancer

by Antti Kukkula, Veera K. Ojala, Lourdes M. Mendez, Lea Sistonen, Klaus Elenius, Maria Sundvall
Published 2021-08-01

Different responses of colorectal cancer cells to alternative sequences of cetuximab and oxaliplatin

by Elli Narvi, Katri Vaparanta, Anna Karrila, Deepankar Chakroborty, Sakari Knuutila, Arto Pulliainen, Maria Sundvall, Klaus Elenius
Published 2018-11-01

Receptor tyrosine kinase profiling of ischemic heart identifies ROR1 as a potential therapeutic target

by Juho Heliste, Anne Jokilammi, Ilkka Paatero, Deepankar Chakroborty, Christoffer Stark, Timo Savunen, Maria Laaksonen, Klaus Elenius
Published 2018-10-01

ERBB4 promoter polymorphism is associated with poor distant disease-free survival in high-risk early breast cancer.

by Kari J Kurppa, Matjaz Rokavec, Maria Sundvall, Pirkko-Liisa Kellokumpu-Lehtinen, Heikki Joensuu, Hiltrud Brauch, Klaus Elenius
Published 2014-01-01

Systemic analysis of gene expression profiles identifies ErbB3 as a potential drug target in pediatric alveolar rhabdomyosarcoma.

by Janne Nordberg, John Patrick Mpindi, Kristiina Iljin, Arto Tapio Pulliainen, Markku Kallajoki, Olli Kallioniemi, Klaus Elenius, Varpu Elenius
Published 2012-01-01

Pim-1 Kinase Expression Predicts Radiation Response in Squamocellular Carcinoma of Head and Neck and Is under the Control of Epidermal Growth Factor Receptor

by Katriina Peltola, Maija Hollmen, Sanna-Mari Maula, Eeva Rainio, Raija Ristamäki, Marjaana Luukkaa, Jouko Sandholm, Maria Sundvall, Klaus Elenius, Päivi J. Koskinen, Reidar Grenman, Sirpa Jalkanen
Published 2009-07-01

Proteolytic processing of ErbB4 in breast cancer.

by Maija Hollmén, Ping Liu, Kari Kurppa, Hans Wildiers, Irene Reinvall, Thijs Vandorpe, Ann Smeets, Karen Deraedt, Tero Vahlberg, Heikki Joensuu, Daniel J Leahy, Patrick Schöffski, Klaus Elenius
Published 2012-01-01