Pathway-specific engineered mouse allograft models functionally recapitulate human serous epithelial ovarian cancer.

Pathway-specific engineered mouse allograft models functionally recapitulate human serous epithelial ovarian cancer.

The high mortality rate from ovarian cancers can be attributed to late-stage diagnosis and lack of effective treatment. Despite enormous effort to develop better targeted therapies, platinum-based chemotherapy still remains the standard of care for ovarian cancer patients, and resistance occurs at a...

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Bibliographic Details
Main Authors: Ludmila Szabova, Sujata Bupp, Muhaymin Kamal, Deborah B Householder, Lidia Hernandez, Jerome J Schlomer, Maureen L Baran, Ming Yi, Robert M Stephens, Christina M Annunziata, Philip L Martin, Terry A Van Dyke, Zoe Weaver Ohler, Simone Difilippantonio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3991711?pdf=render

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http://europepmc.org/articles/PMC3991711?pdf=render

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