High Speed AFM and NanoInfrared Spectroscopy Investigation of Aβ1–42 Peptide Variants and Their Interaction With POPC/SM/Chol/GM1 Model Membranes

High Speed AFM and NanoInfrared Spectroscopy Investigation of Aβ1–42 Peptide Variants and Their Interaction With POPC/SM/Chol/GM1 Model Membranes

Due to an aging population, neurodegenerative diseases such as Alzheimer’s disease (AD) have become a major health issue. In the case of AD, Aβ1–42 peptides have been identified as one of the markers of the disease with the formation of senile plaques via their aggregation, and could play a role in...

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Bibliographic Details
Main Authors: Cecile Feuillie, Eleonore Lambert, Maxime Ewald, Mehdi Azouz, Sarah Henry, Sophie Marsaudon, Christophe Cullin, Sophie Lecomte, Michael Molinari
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
high speed atomic force microscopy
nanoInfrared spectroscopy
peptide Aβ
model lipidic membranes
Alzheimer’s disease
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2020.571696/full

Internet

https://www.frontiersin.org/article/10.3389/fmolb.2020.571696/full

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