Screening for toxic amyloid in yeast exemplifies the role of alternative pathway responsible for cytotoxicity.

by Julien Couthouis, Karine Rébora, Françoise Immel, Karine Berthelot, Michel Castroviejo, Christophe Cullin
Published 2009-01-01

The histone deacetylase inhibitor, Vorinostat, represses hypoxia inducible factor 1 alpha expression through translational inhibition.

by Darren M Hutt, Daniela Martino Roth, Hélène Vignaud, Christophe Cullin, Marion Bouchecareilh
Published 2014-01-01

A yeast model for amyloid-β aggregation exemplifies the role of membrane trafficking and PICALM in cytotoxicity

by Fabien D’Angelo, Hélène Vignaud, Julie Di Martino, Bénédicte Salin, Anne Devin, Christophe Cullin, Christelle Marchal
Published 2013-01-01

Rubber elongation factor (REF), a major allergen component in Hevea brasiliensis latex has amyloid properties.

by Karine Berthelot, Sophie Lecomte, Yannick Estevez, Bénédicte Coulary-Salin, Ahmed Bentaleb, Christophe Cullin, Alain Deffieux, Frédéric Peruch
Published 2012-01-01

The Impact of ESCRT on Aβ1-42 Induced Membrane Lesions in a Yeast Model for Alzheimer’s Disease

by Gernot Fruhmann, Christelle Marchal, Hélène Vignaud, Mathias Verduyckt, Nicolas Talarek, Claudio De Virgilio, Joris Winderickx, Christophe Cullin
Published 2018-11-01

A structure-toxicity study of Aß42 reveals a new anti-parallel aggregation pathway.

by Hélène Vignaud, Claude Bobo, Ioan Lascu, Karin Margareta Sörgjerd, Tamotsu Zako, Mizuo Maeda, Benedicte Salin, Sophie Lecomte, Christophe Cullin
Published 2013-01-01

High Speed AFM and NanoInfrared Spectroscopy Investigation of Aβ1–42 Peptide Variants and Their Interaction With POPC/SM/Chol/GM1 Model Membranes

by Cecile Feuillie, Eleonore Lambert, Maxime Ewald, Mehdi Azouz, Mehdi Azouz, Sarah Henry, Sophie Marsaudon, Christophe Cullin, Sophie Lecomte, Michael Molinari
Published 2020-09-01

ERAD defects and the HFE-H63D variant are associated with increased risk of liver damages in Alpha 1-Antitrypsin Deficiency.

by Philippe Joly, Hélène Vignaud, Julie Di Martino, Mathias Ruiz, Roman Garin, Lioara Restier, Abdelouahed Belmalih, Christelle Marchal, Christophe Cullin, Benoit Arveiler, Patricia Fergelot, Aaron D Gitler, Alain Lachaux, Julien Couthouis, Marion Bouchecareilh
Published 2017-01-01

Guidelines and recommendations on yeast cell death nomenclature

by Didac Carmona-Gutierrez, Maria Anna Bauer, Andreas Zimmermann, Andrés Aguilera, Nicanor Austriaco, Kathryn Ayscough, Rena Balzan, Shoshana Bar-Nun, Antonio Barrientos, Peter Belenky, Marc Blondel, Ralf J. Braun, Michael Breitenbach, William C. Burhans, Sabrina Büttner, Duccio Cavalieri, Michael Chang, Katrina F. Cooper, Manuela Côrte-Real, Vítor Costa, Christophe Cullin, Ian Dawes, Jörn Dengjel, Martin B. Dickman, Tobias Eisenberg, Birthe Fahrenkrog, Nicolas Fasel, Kai-Uwe Fröhlich, Ali Gargouri, Sergio Giannattasio, Paola Goffrini, Campbell W. Gourlay, Chris M. Grant, Michael T. Greenwood, Nicoletta Guaragnella, Thomas Heger, Jürgen Heinisch, Eva Herker, Johannes M. Herrmann, Sebastian Hofer, Antonio Jiménez-Ruiz, Helmut Jungwirth, Katharina Kainz, Dimitrios P. Kontoyiannis, Paula Ludovico, Stéphen Manon, Enzo Martegani, Cristina Mazzoni, Lynn A. Megeney, Chris Meisinger, Jens Nielsen, Thomas Nyström, Heinz D. Osiewacz, Tiago F. Outeiro, Hay-Oak Park, Tobias Pendl, Dina Petranovic, Stephane Picot, Peter Polčic, Peter Polčic, Mark Ramsdale, Mark Rinnerthaler, Patrick Rockenfeller, Christoph Ruckenstuhl, Raffael Schaffrath, Maria Segovia, Fedor F. Severin, Amir Sharon, Stephan J. Sigrist, Cornelia Sommer-Ruck, Maria João Sousa, Johan M. Thevelein, Karin Thevissen, Vladimir Titorenko, Michel B. Toledano, Mick Tuite, F.-Nora Vögtle, Benedikt Westermann, Joris Winderickx, Silke Wissing, Stefan Wölfl, Zhaojie J. Zhang, Richard Y. Zhao, Bing Zhou, Lorenzo Galluzzi, Guido Kroemer, Frank Madeo
Published 2018-01-01