A parsimony approach to biological pathway reconstruction/inference for genomes and metagenomes.

A common biological pathway reconstruction approach -- as implemented by many automatic biological pathway services (such as the KAAS and RAST servers) and the functional annotation of metagenomic sequences -- starts with the identification of protein functions or families (e.g., KO families for the...

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Bibliographic Details
Main Authors: Yuzhen Ye, Thomas G Doak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2714467?pdf=render