Differential Impacts on Host Transcription by ROP and GRA Effectors from the Intracellular Parasite Toxoplasma gondii

Differential Impacts on Host Transcription by ROP and GRA Effectors from the Intracellular Parasite Toxoplasma gondii

This work performs transcriptomic analysis of U-I cells, captures the earliest stage of a host cell’s interaction with Toxoplasma gondii, and dissects the effects of individual classes of parasite effectors on host cell biology.The intracellular parasite Toxoplasma gondii employs a vast array of eff...

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Bibliographic Details
Main Authors: Suchita Rastogi, Yuan Xue, Stephen R. Quake, John C. Boothroyd
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mBio
Subjects:
toxoplasma
effector functions
host-parasite relationship
parasitology
single-cell rna sequencing
Online Access:https://doi.org/10.1128/mBio.00182-20

Internet

https://doi.org/10.1128/mBio.00182-20

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