Have it your way: how polymorphic, injected kinases and pseudokinases enable Toxoplasma to subvert host defenses.

by John C Boothroyd
Published 2013-01-01

Expansion of host range as a driving force in the evolution of Toxoplasma

by John C Boothroyd
Published 2009-03-01

The C-terminus of Toxoplasma RON2 provides the crucial link between AMA1 and the host-associated invasion complex.

by Jessica S Tyler, John C Boothroyd
Published 2011-02-01

Toxoplasma Uses GRA16 To Upregulate Host c-Myc

by Michael W. Panas, John C. Boothroyd
Published 2020-06-01

Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts.

by Yi-Ching Ong, Jon P Boyle, John C Boothroyd
Published 2011-01-01

Differential Impacts on Host Transcription by ROP and GRA Effectors from the Intracellular Parasite Toxoplasma gondii

by Suchita Rastogi, Yuan Xue, Stephen R. Quake, John C. Boothroyd
Published 2020-06-01

An in vitro model of intestinal infection reveals a developmentally regulated transcriptome of Toxoplasma sporozoites and a NF-κB-like signature in infected host cells.

by Pascale S Guiton, Janelle M Sagawa, Heather M Fritz, John C Boothroyd
Published 2017-01-01

Toxoplasma Controls Host Cyclin E Expression through the Use of a Novel MYR1-Dependent Effector Protein, HCE1

by Michael W. Panas, Adit Naor, Alicja M. Cygan, John C. Boothroyd
Published 2019-04-01

Identification of the moving junction complex of Toxoplasma gondii: a collaboration between distinct secretory organelles.

by David L Alexander, Jeffrey Mital, Gary E Ward, Peter Bradley, John C Boothroyd
Published 2005-10-01

4-Bromophenacyl bromide specifically inhibits rhoptry secretion during Toxoplasma invasion.

by Sandeep Ravindran, Melissa B Lodoen, Steven H L Verhelst, Matthew Bogyo, John C Boothroyd
Published 2009-12-01

Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance.

by Heather M Fritz, Paul W Bowyer, Matthew Bogyo, Patricia A Conrad, John C Boothroyd
Published 2012-01-01

A single-parasite transcriptional atlas of Toxoplasma Gondii reveals novel control of antigen expression

by Yuan Xue, Terence C Theisen, Suchita Rastogi, Abel Ferrel, Stephen R Quake, John C Boothroyd
Published 2020-02-01

Toxoplasma gondii infection specifically increases the levels of key host microRNAs.

by Gusti M Zeiner, Kara L Norman, J Michael Thomson, Scott M Hammond, John C Boothroyd
Published 2010-01-01

Toxoplasma gondii sporozoites invade host cells using two novel paralogues of RON2 and AMA1.

by Anna Poukchanski, Heather M Fritz, Michelle L Tonkin, Moritz Treeck, Martin J Boulanger, John C Boothroyd
Published 2013-01-01

A nucleotide sugar transporter involved in glycosylation of the Toxoplasma tissue cyst wall is required for efficient persistence of bradyzoites.

by Carolina E Caffaro, Anita A Koshy, Li Liu, Gusti M Zeiner, Carlos B Hirschberg, John C Boothroyd
Published 2013-01-01

A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins.

by Martin C Fleckenstein, Michael L Reese, Stephanie Könen-Waisman, John C Boothroyd, Jonathan C Howard, Tobias Steinfeldt
Published 2012-01-01

Coimmunoprecipitation with MYR1 Identifies Three Additional Proteins within the Toxoplasma gondii Parasitophorous Vacuole Required for Translocation of Dense Granule Effectors into...

by Alicja M. Cygan, Terence C. Theisen, Alma G. Mendoza, Nicole D. Marino, Michael W. Panas, John C. Boothroyd
Published 2020-02-01

Toxoplasma effector MAF1 mediates recruitment of host mitochondria and impacts the host response.

by Lena Pernas, Yaw Adomako-Ankomah, Anjali J Shastri, Sarah E Ewald, Moritz Treeck, Jon P Boyle, John C Boothroyd
Published 2014-04-01

MYR1-Dependent Effectors Are the Major Drivers of a Host Cell’s Early Response to Toxoplasma, Including Counteracting MYR1-Independent Effects

by Adit Naor, Michael W. Panas, Nicole Marino, Michael J. Coffey, Christopher J. Tonkin, John C. Boothroyd, Louis M. Weiss
Published 2018-04-01

Human Placental Syncytiotrophoblasts Restrict Toxoplasma gondii Attachment and Replication and Respond to Infection by Producing Immunomodulatory Chemokines

by Stephanie E. Ander, Elizabeth N. Rudzki, Nitin Arora, Yoel Sadovsky, Carolyn B. Coyne, Jon P. Boyle, John C. Boothroyd
Published 2018-01-01