Effect of Reduction of Redox Modifications of Cys-Residues in the Na,K-ATPase α1-Subunit on Its Activity

Effect of Reduction of Redox Modifications of Cys-Residues in the Na,K-ATPase α1-Subunit on Its Activity

Sodium-potassium adenosine triphosphatase (Na,K-ATPase) creates a gradient of sodium and potassium ions necessary for the viability of animal cells, and it is extremely sensitive to intracellular redox status. Earlier we found that regulatory glutathionylation determines Na,K-ATPase redox sensitivit...

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Bibliographic Details
Main Authors: Elena A. Dergousova, Irina Yu. Petrushanko, Elizaveta A. Klimanova, Vladimir A. Mitkevich, Rustam H. Ziganshin, Olga D. Lopina, Alexander A. Makarov
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Biomolecules
Subjects:
Na,K-ATPase
α1-subunit
cysteine residues
oxidation
S-glutathionylation
S-nitrosylation
Online Access:http://www.mdpi.com/2218-273X/7/1/18

Internet

http://www.mdpi.com/2218-273X/7/1/18

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