Amyloid β Modification: A Key to the Sporadic Alzheimer's Disease?

by Evgeny P. Barykin, Vladimir A. Mitkevich, Sergey A. Kozin, Alexander A. Makarov
Published 2017-05-01

Direct interaction between ABCA1 and HIV-1 Nef: Molecular modeling and virtual screening for inhibitors

by Alexei A. Adzhubei, Amol Kulkarni, Anna P. Tolstova, Anastasia A. Anashkina, Dmitri Sviridov, Alexander A. Makarov, Michael I. Bukrinsky
Published 2021-01-01

A novel approach for predicting protein S-glutathionylation

by Anastasia A. Anashkina, Yuri M. Poluektov, Vladimir A. Dmitriev, Eugene N. Kuznetsov, Vladimir A. Mitkevich, Alexander A. Makarov, Irina Yu. Petrushanko
Published 2020-09-01

Effect of Reduction of Redox Modifications of Cys-Residues in the Na,K-ATPase α1-Subunit on Its Activity

by Elena A. Dergousova, Irina Yu. Petrushanko, Elizaveta A. Klimanova, Vladimir A. Mitkevich, Rustam H. Ziganshin, Olga D. Lopina, Alexander A. Makarov
Published 2017-02-01

Basal Glutathionylation of Na,K-ATPase α-Subunit Depends on Redox Status of Cells during the Enzyme Biosynthesis

by Vladimir A. Mitkevich, Irina Yu. Petrushanko, Yuri M. Poluektov, Ksenia M. Burnysheva, Valentina A. Lakunina, Anastasia A. Anashkina, Alexander A. Makarov
Published 2016-01-01

Oxidation of Са2+-Binding Domain of NADPH Oxidase 5 (NOX5): Toward Understanding the Mechanism of Inactivation of NOX5 by ROS.

by Irina Yu Petrushanko, Vladimir M Lobachev, Alexey S Kononikhin, Alexander A Makarov, Francois Devred, Hervé Kovacic, Aslan A Kubatiev, Philipp O Tsvetkov
Published 2016-01-01

Amyloid-β peptides slightly affect lifespan or antimicrobial peptide gene expression in Drosophila melanogaster

by Mikhail V. Shaposhnikov, Nadezhda V. Zemskaya, Lyubov А. Koval, Natalya R. Minnikhanova, Olga I. Kechko, Vladimir A. Mitkevich, Alexander A. Makarov, Alexey А. Moskalev
Published 2020-10-01

The English (H6R) Mutation of the Alzheimer’s Disease Amyloid-β Peptide Modulates Its Zinc-Induced Aggregation

by Sergey P. Radko, Svetlana A. Khmeleva, Dmitry N. Kaluzhny, Olga I. Kechko, Yana Y. Kiseleva, Sergey A. Kozin, Vladimir A. Mitkevich, Alexander A. Makarov
Published 2020-06-01

The Effects of Endogenous Non-Peptide Molecule Isatin and Hydrogen Peroxide on Proteomic Profiling of Rat Brain Amyloid-β Binding Proteins: Relevance to Alzheimer’s Disease?

by Alexei E. Medvedev, Olga A. Buneeva, Arthur T. Kopylov, Oksana V. Gnedenko, Marina V. Medvedeva, Sergey A. Kozin, Alexis S. Ivanov, Victor G. Zgoda, Alexander A. Makarov
Published 2014-12-01

Phosphorylation of the Amyloid-Beta Peptide Inhibits Zinc-Dependent Aggregation, Prevents Na,K-ATPase Inhibition, and Reduces Cerebral Plaque Deposition

by Evgeny P. Barykin, Irina Y. Petrushanko, Sergey A. Kozin, Georgy B. Telegin, Alexander S. Chernov, Olga D. Lopina, Sergey P. Radko, Vladimir A. Mitkevich, Alexander A. Makarov
Published 2018-08-01

Intravenously Injected Amyloid-β Peptide With Isomerized Asp7 and Phosphorylated Ser8 Residues Inhibits Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice Model of Alzheimer’s Dise...

by Sergey A. Kozin, Evgeny P. Barykin, Georgy B. Telegin, Alexander S. Chernov, Alexei A. Adzhubei, Sergey P. Radko, Sergey P. Radko, Vladimir A. Mitkevich, Alexander A. Makarov
Published 2018-08-01

Tetrapeptide Ac-HAEE-NH₂ Protects α4β2 nAChR from Inhibition by Aβ

by Evgeny P. Barykin, Aleksandra I. Garifulina, Anna P. Tolstova, Anastasia A. Anashkina, Alexei A. Adzhubei, Yuri V. Mezentsev, Irina V. Shelukhina, Sergey A. Kozin, Victor I. Tsetlin, Alexander A. Makarov
Published 2020-08-01

HCV Core Protein Uses Multiple Mechanisms to Induce Oxidative Stress in Human Hepatoma Huh7 Cells

by Alexander V. Ivanov, Olga A. Smirnova, Irina Y. Petrushanko, Olga N. Ivanova, Inna L. Karpenko, Ekaterina Alekseeva, Irina Sominskaya, Alexander A. Makarov, Birke Bartosch, Sergey N. Kochetkov, Maria G. Isaguliants
Published 2015-05-01

Pharmacokinetics and Molecular Modeling Indicate nAChRα4-Derived Peptide HAEE Goes through the Blood–Brain Barrier

by Yurii A. Zolotarev, Vladimir A. Mitkevich, Stanislav I. Shram, Alexei A. Adzhubei, Anna P. Tolstova, Oleg B. Talibov, Alexander K. Dadayan, Nikolai F. Myasoyedov, Alexander A. Makarov, Sergey A. Kozin
Published 2021-06-01

Cysteine residues 244 and 458–459 within the catalytic subunit of Na,K-ATPase control the enzyme's hydrolytic and signaling function under hypoxic conditions

by Irina Yu. Petrushanko, Vladimir A. Mitkevich, Valentina A. Lakunina, Anastasia A. Anashkina, Pavel V. Spirin, Peter M. Rubtsov, Vladimir S. Prassolov, Nikolay B. Bogdanov, Pascal Hänggi, William Fuller, Alexander A. Makarov, Anna Bogdanova
Published 2017-10-01

Isomerization of Asp7 in Beta-Amyloid Enhances Inhibition of the α7 Nicotinic Receptor and Promotes Neurotoxicity

by Evgeny P. Barykin, Alexandra I. Garifulina, Elena V. Kruykova, Ekaterina N. Spirova, Anastasia A. Anashkina, Alexei A. Adzhubei, Irina V. Shelukhina, Igor E. Kasheverov, Vladimir A. Mitkevich, Sergey A. Kozin, Michael Hollmann, Victor I. Tsetlin, Alexander A. Makarov
Published 2019-07-01