Methods for integration of transcriptomic data in genome-scale metabolic models

Several computational methods have been developed that integrate transcriptomic data with genome-scale metabolic reconstructions to infer condition-specific system-wide intracellular metabolic flux distributions. In this mini-review, we describe each of these methods published to date with categoriz...

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Bibliographic Details
Main Authors: Min Kyung Kim, Desmond S. Lun
Format: Article
Language:English
Published: Elsevier 2014-08-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037014000245