Reciprocal c-di-GMP signaling: Incomplete flagellum biogenesis triggers c-di-GMP signaling pathways that promote biofilm formation.

The assembly status of the V. cholerae flagellum regulates biofilm formation, suggesting that the bacterium senses a lack of movement to commit to a sessile lifestyle. Motility and biofilm formation are inversely regulated by the second messenger molecule cyclic dimeric guanosine monophosphate (c-di...

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Bibliographic Details
Main Authors: Daniel C Wu, David Zamorano-Sánchez, Fernando A Pagliai, Jin Hwan Park, Kyle A Floyd, Calvin K Lee, Giordan Kitts, Christopher B Rose, Eric M Bilotta, Gerard C L Wong, Fitnat H Yildiz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008703