Functional Reciprocity of Amyloids and Antimicrobial Peptides: Rethinking the Role of Supramolecular Assembly in Host Defense, Immune Activation, and Inflammation

by Ernest Y. Lee, Ernest Y. Lee, Yashes Srinivasan, Jaime de Anda, Lauren K. Nicastro, Çagla Tükel, Gerard C. L. Wong, Gerard C. L. Wong, Gerard C. L. Wong
Published 2020-07-01

Reinventing Cell Penetrating Peptides Using Glycosylated Methionine Sulfonium Ion Sequences

by Jessica R. Kramer, Nathan W. Schmidt, Kristine M. Mayle, Daniel T. Kamei, Gerard C. L. Wong, Timothy J. Deming
Published 2015-04-01

Functional Specialization in Vibrio cholerae Diguanylate Cyclases: Distinct Modes of Motility Suppression and c-di-GMP Production

by David Zamorano-Sánchez, Wujing Xian, Calvin K. Lee, Mauro Salinas, Wiriya Thongsomboon, Lynette Cegelski, Gerard C. L. Wong, Fitnat H. Yildiz
Published 2019-04-01

The pel polysaccharide can serve a structural and protective role in the biofilm matrix of Pseudomonas aeruginosa.

by Kelly M Colvin, Vernita D Gordon, Keiji Murakami, Bradley R Borlee, Daniel J Wozniak, Gerard C L Wong, Matthew R Parsek
Published 2011-01-01

Discovery of Novel Type II Bacteriocins Using a New High-Dimensional Bioinformatic Algorithm

by Nannette Y. Yount, Nannette Y. Yount, Nannette Y. Yount, David C. Weaver, Jaime de Anda, Jaime de Anda, Ernest Y. Lee, Ernest Y. Lee, Michelle W. Lee, Michelle W. Lee, Gerard C. L. Wong, Gerard C. L. Wong, Michael R. Yeaman, Michael R. Yeaman, Michael R. Yeaman, Michael R. Yeaman
Published 2020-09-01

C-di-GMP Regulates Motile to Sessile Transition by Modulating MshA Pili Biogenesis and Near-Surface Motility Behavior in Vibrio cholerae.

by Christopher J Jones, Andrew Utada, Kimberly R Davis, Wiriya Thongsomboon, David Zamorano Sanchez, Vinita Banakar, Lynette Cegelski, Gerard C L Wong, Fitnat H Yildiz
Published 2015-10-01

Helical antimicrobial peptides assemble into protofibril scaffolds that present ordered dsDNA to TLR9

by Ernest Y. Lee, Changsheng Zhang, Jeremy Di Domizio, Fan Jin, Will Connell, Mandy Hung, Nicolas Malkoff, Veronica Veksler, Michel Gilliet, Pengyu Ren, Gerard C. L. Wong
Published 2019-03-01

Molecular Motor Dnm1 Synergistically Induces Membrane Curvature To Facilitate Mitochondrial Fission

by Michelle W. Lee, Ernest Y. Lee, Ghee Hwee Lai, Nolan W. Kennedy, Ammon E. Posey, Wujing Xian, Andrew L. Ferguson, R. Blake Hill, Gerard C. L. Wong
Published 2017-11-01

Bacterial amyloid curli acts as a carrier for DNA to elicit an autoimmune response via TLR2 and TLR9.

by Sarah A Tursi, Ernest Y Lee, Nicole J Medeiros, Michael H Lee, Lauren K Nicastro, Bettina Buttaro, Stefania Gallucci, Ronald Paul Wilson, Gerard C L Wong, Çagla Tükel
Published 2017-04-01

Reciprocal c-di-GMP signaling: Incomplete flagellum biogenesis triggers c-di-GMP signaling pathways that promote biofilm formation.

by Daniel C Wu, David Zamorano-Sánchez, Fernando A Pagliai, Jin Hwan Park, Kyle A Floyd, Calvin K Lee, Giordan Kitts, Christopher B Rose, Eric M Bilotta, Gerard C L Wong, Fitnat H Yildiz
Published 2020-03-01

S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages.

by Susan Realegeno, Kindra M Kelly-Scumpia, Angeline Tilly Dang, Jing Lu, Rosane Teles, Philip T Liu, Mirjam Schenk, Ernest Y Lee, Nathan W Schmidt, Gerard C L Wong, Euzenir N Sarno, Thomas H Rea, Maria T Ochoa, Matteo Pellegrini, Robert L Modlin
Published 2016-06-01

Social Cooperativity of Bacteria during Reversible Surface Attachment in Young Biofilms: a Quantitative Comparison of Pseudomonas aeruginosa PA14 and PAO1

by Calvin K. Lee, Jérémy Vachier, Jaime de Anda, Kun Zhao, Amy E. Baker, Rachel R. Bennett, Catherine R. Armbruster, Kimberley A. Lewis, Rebecca L. Tarnopol, Charles J. Lomba, Deborah A. Hogan, Matthew R. Parsek, George A. O’Toole, Ramin Golestanian, Gerard C. L. Wong
Published 2020-02-01

CXCL4 assembles DNA into liquid crystalline complexes to amplify TLR9-mediated interferon-α production in systemic sclerosis

by Roberto Lande, Ernest Y. Lee, Raffaella Palazzo, Barbara Marinari, Immacolata Pietraforte, Giancarlo Santiago Santos, Yves Mattenberger, Francesca Spadaro, Katia Stefanantoni, Nicoletta Iannace, Aleksandra Maria Dufour, Mario Falchi, Manuela Bianco, Elisabetta Botti, Luca Bianchi, Montserrat Alvarez, Valeria Riccieri, Marie-Elise Truchetet, Gerard C.L. Wong, Carlo Chizzolini, Loredana Frasca
Published 2019-05-01

c-di-GMP modulates type IV MSHA pilus retraction and surface attachment in Vibrio cholerae

by Kyle A. Floyd, Calvin K. Lee, Wujing Xian, Mahmoud Nametalla, Aneesa Valentine, Benjamin Crair, Shiwei Zhu, Hannah Q. Hughes, Jennifer L. Chlebek, Daniel C. Wu, Jin Hwan Park, Ali M. Farhat, Charles J. Lomba, Courtney K. Ellison, Yves V. Brun, Javier Campos-Gomez, Ankur B. Dalia, Jun Liu, Nicolas Biais, Gerard C. L. Wong, Fitnat H. Yildiz
Published 2020-03-01