Immune Mechanisms Underlying Susceptibility to Endotoxin Shock in Aged Hosts: Implication in Age-Augmented Generalized Shwartzman Reaction

Immune Mechanisms Underlying Susceptibility to Endotoxin Shock in Aged Hosts: Implication in Age-Augmented Generalized Shwartzman Reaction

In recent decades, the elderly population has been rapidly increasing in many countries. Such patients are susceptible to Gram-negative septic shock, namely endotoxin shock. Mortality due to endotoxin shock remains high despite recent advances in medical care. The generalized Shwartzman reaction is...

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Bibliographic Details
Main Authors: Manabu Kinoshita, Masahiro Nakashima, Hiroyuki Nakashima, Shuhji Seki
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
LPS
septic shock
elderly
innate lymphocytes
endotoxin tolerance
Online Access:https://www.mdpi.com/1422-0067/20/13/3260

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https://www.mdpi.com/1422-0067/20/13/3260

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