Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice

Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice

We sought to determine if sex impacts the cognitive and neuropathological phenotype of the 3xTg-AD mice. We find that male and female 3xTg-AD mice show comparable impairments on Morris water maze (MWM) and inhibitory avoidance (IA) at 4 months. Shortly thereafter, however, the cognitive performance...

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Bibliographic Details
Main Authors: Lani K. Clinton, Lauren M. Billings, Kim N. Green, Antonella Caccamo, Jerry Ngo, Salvatore Oddo, James L. McGaugh, Frank M. LaFerla
Format: Article
Language:English
Published: Elsevier 2007-10-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107001350

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http://www.sciencedirect.com/science/article/pii/S0969996107001350

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