Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits.

by Smita Majumder, Arlan Richardson, Randy Strong, Salvatore Oddo
Published 2011-01-01

Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease.

by José J Rodríguez, Victoria C Jones, Masashi Tabuchi, Stuart M Allan, Elysse M Knight, Frank M LaFerla, Salvatore Oddo, Alexei Verkhratsky
Published 2008-01-01

Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice

by Lani K. Clinton, Lauren M. Billings, Kim N. Green, Antonella Caccamo, Jerry Ngo, Salvatore Oddo, James L. McGaugh, Frank M. LaFerla
Published 2007-10-01

Chronic temporal lobe epilepsy is associated with enhanced Alzheimer-like neuropathology in 3×Tg-AD mice.

by Xiao-Xin Yan, Yan Cai, Jarod Shelton, Si-Hao Deng, Xue-Gang Luo, Salvatore Oddo, Frank M Laferla, Huaibin Cai, Gregory M Rose, Peter R Patrylo
Published 2012-01-01

The collagen chaperone HSP47 is a new interactor of APP that affects the levels of extracellular beta-amyloid peptides.

by Federico T Bianchi, Paola Camera, Ugo Ala, Daniele Imperiale, Antonio Migheli, Enrica Boda, Filippo Tempia, Gaia Berto, Ylenia Bosio, Salvatore Oddo, Frank M LaFerla, Stefano Taraglio, Carlos G Dotti, Ferdinando Di Cunto
Published 2011-01-01

Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology

by Fiona E. McAlpine, Jae-Kyung Lee, Ashley S. Harms, Kelly A. Ruhn, Mathew Blurton-Jones, John Hong, Pritam Das, Todd E. Golde, Frank M. LaFerla, Salvatore Oddo, Armin Blesch, Malú G. Tansey
Published 2009-04-01