Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function.

Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function.

Investigators have linked rare copy number variation (CNVs) to neuropsychiatric diseases, such as schizophrenia. One hypothesis is that CNV events cause disease by affecting genes with specific brain functions. Under these circumstances, we expect that CNV events in cases should impact brain-functio...

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Bibliographic Details
Main Authors: Soumya Raychaudhuri, Joshua M Korn, Steven A McCarroll, International Schizophrenia Consortium, David Altshuler, Pamela Sklar, Shaun Purcell, Mark J Daly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2936523?pdf=render

Internet

http://europepmc.org/articles/PMC2936523?pdf=render

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