Population Genomics of <italic toggle="yes">emm4</italic> Group A <named-content content-type="genus-species">Streptococcus</named-content> Reveals Progressive Replacement with a Hypervirulent Clone in North America

Population Genomics of <italic toggle="yes">emm4</italic> Group A <named-content content-type="genus-species">Streptococcus</named-content> Reveals Progressive Replacement with a Hypervirulent Clone in North America

ABSTRACT Clonal replacement is a major driver for changes in bacterial disease epidemiology. Recently, it has been proposed that episodic emergence of novel, hypervirulent clones of group A Streptococcus (GAS) results from acquisition of a 36-kb DNA region leading to increased expression of the cyto...

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Bibliographic Details
Main Authors: Sruti DebRoy, Misu Sanson, Brittany Shah, Shirjana Regmi, Luis Alberto Vega, Chioma Odo, Pranoti Sahasrabhojane, Allison McGeer, Gregory J. Tyrrell, Nahuel Fittipaldi, Samuel A. Shelburne, Anthony R. Flores
Format: Article
Language:English
Published: American Society for Microbiology 2021-08-01
Series:mSystems
Subjects:
M type
evolution
exotoxin
genomics
group A Streptococcus
population genetics
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00495-21

Internet

https://journals.asm.org/doi/10.1128/mSystems.00495-21

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