Dietary compound proanthocyanidins from Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves inhibit angiogenesis and regulate cell cycle of cisplatin-resistant ovarian cancer cells via targeting Akt pathway

Dietary compound proanthocyanidins from Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves inhibit angiogenesis and regulate cell cycle of cisplatin-resistant ovarian cancer cells via targeting Akt pathway

Ovarian cancer is the leading cause of death from gynecological malignancy and natural products have drawn great attention for cancer treatment. Chinese bayberry leaves proanthocyanidin (BLPs) with epigallocatechin-3-O-gallate (EGCG) as its terminal and major extension units is unusual in the plant...

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Bibliographic Details
Main Authors: Yu Zhang, Shiguo Chen, Chaoyang Wei, Gary O. Rankin, Yon Rojanasakul, Ning Ren, Xingqian Ye, Yi Charlie Chen
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Journal of Functional Foods
Subjects:
Proanthocyanidins
Chinese bayberry leaves
Ovarian cancer
Angiogenesis
Cell cycle
Akt
Online Access:http://www.sciencedirect.com/science/article/pii/S175646461730717X

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http://www.sciencedirect.com/science/article/pii/S175646461730717X

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