FISHtrees 3.0: Tumor Phylogenetics Using a Ploidy Probe.

Advances in fluorescence in situ hybridization (FISH) make it feasible to detect multiple copy-number changes in hundreds of cells of solid tumors. Studies using FISH, sequencing, and other technologies have revealed substantial intra-tumor heterogeneity. The evolution of subclones in tumors may be...

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Bibliographic Details
Main Authors: E Michael Gertz, Salim Akhter Chowdhury, Woei-Jyh Lee, Darawalee Wangsa, Kerstin Heselmeyer-Haddad, Thomas Ried, Russell Schwartz, Alejandro A Schäffer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0158569