Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease

Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease

The immune-mediated tissue destruction of graft-vs-host disease (GvHD) remains a major barrier to greater use of hematopoietic stem cell transplantation (HSCT). Mesenchymal stem cells (MSCs) have intrinsic immunosuppressive qualities and are being actively investigated as a therapeutic strategy for...

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Bibliographic Details
Main Authors: E. Ilker Ozay, Jyothi Vijayaraghavan, Gabriela Gonzalez-Perez, Sudarvili Shanthalingam, Heather L. Sherman, Daniel T. Garrigan, Jr., Karthik Chandiran, Joe A. Torres, Barbara A. Osborne, Gregory N. Tew, Igor I. Slukvin, Ross A. Macdonald, Kilian Kelly, Lisa M. Minter
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506119300315

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http://www.sciencedirect.com/science/article/pii/S1873506119300315

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