A defined, feeder-free, serum-free system to generate in vitro hematopoietic progenitors and differentiated blood cells from hESCs and hiPSCs.

by Giorgia Salvagiotto, Sarah Burton, Christine A Daigh, Deepika Rajesh, Igor I Slukvin, Nicholas J Seay
Published 2011-03-01

CCR5 Disruption in Induced Pluripotent Stem Cells Using CRISPR/Cas9 Provides Selective Resistance of Immune Cells to CCR5-tropic HIV-1 Virus

by HyunJun Kang, Petra Minder, Mi Ae Park, Walatta-Tseyon Mesquitta, Bruce E Torbett, Igor I Slukvin
Published 2015-01-01

GSK3β Inhibition Promotes Efficient Myeloid and Lymphoid Hematopoiesis from Non-human Primate-Induced Pluripotent Stem Cells

by Saritha S. D'Souza, John Maufort, Akhilesh Kumar, Jiuchun Zhang, Kimberley Smuga-Otto, James A. Thomson, Igor I. Slukvin
Published 2016-02-01

GATA2 Is Dispensable for Specification of Hemogenic Endothelium but Promotes Endothelial-to-Hematopoietic Transition

by HyunJun Kang, Walatta-Tseyon Mesquitta, Ho Sun Jung, Oleg V. Moskvin, James A. Thomson, Igor I. Slukvin
Published 2018-07-01

Activation of the Arterial Program Drives Development of Definitive Hemogenic Endothelium with Lymphoid Potential

by Mi Ae Park, Akhilesh Kumar, Ho Sun Jung, Gene Uenishi, Oleg V. Moskvin, James A. Thomson, Igor I. Slukvin
Published 2018-05-01

Nonirradiated NOD,B6.SCID Il2rγ−/− KitW41/W41 (NBSGW) Mice Support Multilineage Engraftment of Human Hematopoietic Cells

by Brian E. McIntosh, Matthew E. Brown, Bret M. Duffin, John P. Maufort, David T. Vereide, Igor I. Slukvin, James A. Thomson
Published 2015-02-01

Specification and Diversification of Pericytes and Smooth Muscle Cells from Mesenchymoangioblasts

by Akhilesh Kumar, Saritha Sandra D’Souza, Oleg V. Moskvin, Huishi Toh, Bowen Wang, Jue Zhang, Scott Swanson, Lian-Wang Guo, James A. Thomson, Igor I. Slukvin
Published 2017-05-01

Identification of the Hemogenic Endothelial Progenitor and Its Direct Precursor in Human Pluripotent Stem Cell Differentiation Cultures

by Kyung-Dal Choi, Maxim A. Vodyanik, Padma Priya Togarrati, Kran Suknuntha, Akhilesh Kumar, Fnu Samarjeet, Mitchell D. Probasco, Shulan Tian, Ron Stewart, James A. Thomson, Igor I. Slukvin
Published 2012-09-01

Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease

by E. Ilker Ozay, Jyothi Vijayaraghavan, Gabriela Gonzalez-Perez, Sudarvili Shanthalingam, Heather L. Sherman, Daniel T. Garrigan, Jr., Karthik Chandiran, Joe A. Torres, Barbara A. Osborne, Gregory N. Tew, Igor I. Slukvin, Ross A. Macdonald, Kilian Kelly, Lisa M. Minter
Published 2019-03-01

NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells

by Gene I. Uenishi, Ho Sun Jung, Akhilesh Kumar, Mi Ae Park, Brandon K. Hadland, Ethan McLeod, Matthew Raymond, Oleg Moskvin, Catherine E. Zimmerman, Derek J. Theisen, Scott Swanson, Owen J. Tamplin, Leonard I. Zon, James A. Thomson, Irwin D. Bernstein, Igor I. Slukvin
Published 2018-05-01