A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues.

The modification of DNA by methylation is an important epigenetic mechanism that affects the spatial and temporal regulation of gene expression. Methylation patterns have been described in many contexts within and across a range of species. However, the extent to which changes in methylation might u...

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Bibliographic Details
Main Authors: Athma A Pai, Jordana T Bell, John C Marioni, Jonathan K Pritchard, Yoav Gilad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3044686?pdf=render