First field efficacy trial of the ChAd63 MVA ME-TRAP vectored malaria vaccine candidate in 5-17 months old infants and children.

<h4>Background</h4>Heterologous prime boost immunization with chimpanzee adenovirus 63 (ChAd63) and Modified Vaccinia Virus Ankara (MVA) vectored vaccines is a strategy previously shown to provide substantial protective efficacy against P. falciparum infection in United Kingdom adult Pha...

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Bibliographic Details
Main Authors: Alfred B Tiono, Issa Nébié, Nicholas Anagnostou, Aboubacar S Coulibaly, Georgina Bowyer, Erika Lam, Edith C Bougouma, Alphonse Ouedraogo, Jean Baptist B Yaro, Aïssata Barry, Rachel Roberts, Tommy Rampling, Carly Bliss, Susanne Hodgson, Alison Lawrie, Amidou Ouedraogo, Egeruan Babatunde Imoukhuede, Katie J Ewer, Nicola K Viebig, Amidou Diarra, Odile Leroy, Philip Bejon, Adrian V S Hill, Sodiomon B Sirima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0208328