Colocalization of 14-3-3 proteins with SOD1 in Lewy body-like hyaline inclusions in familial amyotrophic lateral sclerosis cases and the animal model.

Colocalization of 14-3-3 proteins with SOD1 in Lewy body-like hyaline inclusions in familial amyotrophic lateral sclerosis cases and the animal model.

Cu/Zn superoxide dismutase (SOD1) is a major component of Lewy body-like hyaline inclusion (LBHI) found in the postmortem tissue of SOD1-linked familial amyotrophic lateral sclerosis (FALS) patients. In our recent studies, 14-3-3 proteins have been found in the ubiquitinated inclusions inside the an...

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Bibliographic Details
Main Authors: Yoko Okamoto, Yoshitomo Shirakashi, Masafumi Ihara, Makoto Urushitani, Miki Oono, Yasuhiro Kawamoto, Hirofumi Yamashita, Shun Shimohama, Shinsuke Kato, Asao Hirano, Hidekazu Tomimoto, Hidefumi Ito, Ryosuke Takahashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3105059?pdf=render

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http://europepmc.org/articles/PMC3105059?pdf=render

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