LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion

Summary: The Met/hepatocyte growth factor (HGF) receptor tyrosine kinase (RTK) is deregulated in many cancers and is a recognized target for cancer therapies. Following HGF stimulation, the signaling output of Met is tightly controlled by receptor internalization and sorting for degradation or recyc...

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Bibliographic Details
Main Authors: Emily S. Bell, Paula Pinto Coelho, Colin D.H. Ratcliffe, Charles V. Rajadurai, Pascal Peschard, Richard Vaillancourt, Dongmei Zuo, Morag Park
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719315542