Metabolic Flexibility Is a Determinant of Breast Cancer Heterogeneity and Progression

by Marina Fukano, Morag Park, Geneviève Deblois
Published 2021-09-01

Cholesterol-Induced Metabolic Reprogramming in Breast Cancer Cells Is Mediated via the ERRα Pathway

by Faegheh Ghanbari, Anne-Marie Fortier, Morag Park, Anie Philip
Published 2021-05-01

Abl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and Motility.

by Ran Li, Jennifer F Knight, Morag Park, Ann Marie Pendergast
Published 2015-01-01

Predicting Relapse in Patients With Triple Negative Breast Cancer (TNBC) Using a Deep-Learning Approach

by Guangyuan Yu, Guangyuan Yu, Xuefei Li, Ting-Fang He, Tina Gruosso, Tina Gruosso, Dongmei Zuo, Margarita Souleimanova, Valentina Muñoz Ramos, Atilla Omeroglu, Sarkis Meterissian, Sarkis Meterissian, Marie-Christine Guiot, Marie-Christine Guiot, Li Yang, Yuan Yuan, Morag Park, Morag Park, Morag Park, Peter P. Lee, Herbert Levine, Herbert Levine
Published 2020-09-01

Correction: The Lysine Acetyltransferase Activator Brpf1 Governs Dentate Gyrus Development through Neural Stem Cells and Progenitors.

by Linya You, Kezhi Yan, Jinfeng Zou, Hong Zhao, Nicholas R Bertos, Morag Park, Edwin Wang, Xiang-Jiao Yang
Published 2015-06-01

ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties.

by April A N Rose, Matthew G Annis, Zhifeng Dong, Francois Pepin, Michael Hallett, Morag Park, Peter M Siegel
Published 2010-08-01

The lysine acetyltransferase activator Brpf1 governs dentate gyrus development through neural stem cells and progenitors.

by Linya You, Kezhi Yan, Jinfeng Zou, Hong Zhao, Nicholas R Bertos, Morag Park, Edwin Wang, Xiang-Jiao Yang
Published 2015-03-01

LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion

by Emily S. Bell, Paula Pinto Coelho, Colin D.H. Ratcliffe, Charles V. Rajadurai, Pascal Peschard, Richard Vaillancourt, Dongmei Zuo, Morag Park
Published 2019-12-01

Lineage Specification from Prostate Progenitor Cells Requires Gata3-Dependent Mitotic Spindle Orientation

by Maxwell E.R. Shafer, Alana H.T. Nguyen, Mathieu Tremblay, Sophie Viala, Mélanie Béland, Nicholas R. Bertos, Morag Park, Maxime Bouchard
Published 2017-04-01

Autocrine Activation of the Wnt/β-Catenin Pathway by CUX1 and GLIS1 in Breast Cancers

by Charles Vadnais, Peiman Shooshtarizadeh, Charles V. Rajadurai, Robert Lesurf, Laura Hulea, Sayeh Davoudi, Chantal Cadieux, Michael Hallett, Morag Park, Alain Nepveu
Published 2014-09-01

In silico ascription of gene expression differences to tumor and stromal cells in a model to study impact on breast cancer outcome.

by Simen Myhre, Hayat Mohammed, Trine Tramm, Jan Alsner, Greg Finak, Morag Park, Jens Overgaard, Anne-Lise Børresen-Dale, Arnoldo Frigessi, Therese Sørlie
Published 2010-01-01

p66ShcA potentiates the cytotoxic response of triple-negative breast cancers to PARP inhibitors

by Eduardo Cepeda Cañedo, Stephanie Totten, Ryuhjin Ahn, Paul Savage, Deanna MacNeil, Jesse Hudson, Chantal Autexier, Genevieve Deblois, Morag Park, Michael Witcher, Josie Ursini-Siegel
Published 2021-02-01

Co-dependency for MET and FGFR1 in basal triple-negative breast cancers

by Vanessa Y. C. Sung, Jennifer F. Knight, Radia M. Johnson, Yaakov E. Stern, Sadiq M. Saleh, Paul Savage, Anie Monast, Dongmei Zuo, Stéphanie Duhamel, Morag Park
Published 2021-03-01

Dispersible hydrogel force sensors reveal patterns of solid mechanical stress in multicellular spheroid cultures

by Wontae Lee, Nikita Kalashnikov, Stephanie Mok, Ruba Halaoui, Elena Kuzmin, Andrew J. Putnam, Shuichi Takayama, Morag Park, Luke McCaffrey, Ruogang Zhao, Richard L. Leask, Christopher Moraes
Published 2019-01-01

Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program

by Alison Hirukawa, Harvey W. Smith, Dongmei Zuo, Catherine R. Dufour, Paul Savage, Nicholas Bertos, Radia M. Johnson, Tung Bui, Guillaume Bourque, Mark Basik, Vincent Giguère, Morag Park, William J. Muller
Published 2018-06-01

ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer

by Geneviève Deblois, Harvey W. Smith, Ingrid S. Tam, Simon-Pierre Gravel, Maxime Caron, Paul Savage, David P. Labbé, Louis R. Bégin, Michel L. Tremblay, Morag Park, Guillaume Bourque, Julie St-Pierre, William J. Muller, Vincent Giguère
Published 2016-07-01

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression

by Marie-Anne Goyette, Stéphanie Duhamel, Léo Aubert, Ariane Pelletier, Paul Savage, Marie-Pier Thibault, Radia Marie Johnson, Peter Carmeliet, Mark Basik, Louis Gaboury, William J. Muller, Morag Park, Philippe P. Roux, Jean-Philippe Gratton, Jean-François Côté
Published 2018-05-01

Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy

by Alison Hirukawa, Salendra Singh, Jarey Wang, Jonathan P. Rennhack, Matthew Swiatnicki, Virginie Sanguin-Gendreau, Dongmei Zuo, Kamilia Daldoul, Cynthia Lavoie, Morag Park, Eran R. Andrechek, Thomas F. Westbrook, Lyndsay N. Harris, Vinay Varadan, Harvey W. Smith, William J. Muller
Published 2019-10-01

The Prognostic Ease and Difficulty of Invasive Breast Carcinoma

by Ali Tofigh, Matthew Suderman, Eric R. Paquet, Julie Livingstone, Nicholas Bertos, Sadiq M. Saleh, Hong Zhao, Margarita Souleimanova, Sean Cory, Robert Lesurf, Solmaz Shahalizadeh, Norberto Garcia Lopez, Yasser Riazalhosseini, Atilla Omeroglu, Josie Ursini-Siegel, Morag Park, Vanessa Dumeaux, Michael Hallett
Published 2014-10-01

Activation of the pattern recognition receptor NOD1 augments colon cancer metastasis

by Henry Y. Jiang, Sara Najmeh, Guy Martel, Elyse MacFadden-Murphy, Raquel Farias, Paul Savage, Arielle Leone, Lucie Roussel, Jonathan Cools-Lartigue, Stephen Gowing, Julie Berube, Betty Giannias, France Bourdeau, Carlos H. F. Chan, Jonathan D. Spicer, Rebecca McClure, Morag Park, Simon Rousseau, Lorenzo E. Ferri
Published 2020-01-01