Machine learning uncovers cell identity regulator by histone code
Identification of genes that determine and regulate cell identity remains challenging. Here, the authors use machine learning to identify cell identity genes and master regulator transcription factors based on gene expression profiles and histone modifications.
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-16539-4 |