Therapeutic transdifferentiation of human fibroblasts into endothelial cells using forced expression of lineage-specific transcription factors

by Wing Tak Wong, John P Cooke
Published 2016-02-01

mRNA-Enhanced Cell Therapy and Cardiovascular Regeneration

by Palas K. Chanda, Roman Sukhovershin, John P. Cooke
Published 2021-01-01

Bioluminescence Imaging of Stem Cell-Based Therapeutics for Vascular Regeneration

by Ngan F. Huang, Janet Okogbaa, Anna Babakhanyan, John P. Cooke
Published 2012-01-01

Optimal ROS Signaling Is Critical for Nuclear Reprogramming

by Gang Zhou, Shu Meng, Yanhui Li, Yohannes T. Ghebre, John P. Cooke
Published 2016-05-01

Progeria and accelerated cardiovascular aging

by Brandon K Walther, Yanhui Li, Rajarajan Amirthalingam Thandavarayan, John P Cooke
Published 2018-01-01

Self-reported history of childhood smoking is associated with an increased risk for peripheral arterial disease independent of lifetime smoking burden.

by James R Priest, Kevin T Nead, Mackenzie R Wehner, John P Cooke, Nicholas J Leeper
Published 2014-01-01

The Limitless Future of RNA Therapeutics

by Tulsi Ram Damase, Roman Sukhovershin, Christian Boada, Francesca Taraballi, Francesca Taraballi, Roderic I. Pettigrew, John P. Cooke
Published 2021-03-01

Induced endothelial cells from peripheral arterial disease patients and neonatal fibroblasts have comparable angiogenic properties

by Jack D. Hywood, Sara Sadeghipour, Zoe E. Clayton, Jun Yuan, Colleen Stubbs, Jack W. T. Wong, John P. Cooke, Sanjay Patel
Published 2021-01-01

Proton Pump Inhibitor Usage and the Risk of Myocardial Infarction in the General Population.

by Nigam H Shah, Paea LePendu, Anna Bauer-Mehren, Yohannes T Ghebremariam, Srinivasan V Iyer, Jake Marcus, Kevin T Nead, John P Cooke, Nicholas J Leeper
Published 2015-01-01

TADsplimer reveals splits and mergers of topologically associating domains for epigenetic regulation of transcription

by Guangyu Wang, Qingshu Meng, Bo Xia, Shuo Zhang, Jie Lv, Dongyu Zhao, Yanqiang Li, Xin Wang, Lili Zhang, John P. Cooke, Qi Cao, Kaifu Chen
Published 2020-04-01

Role of Endothelial and Mesenchymal Cell Transitions in Heart Failure and Recovery Thereafter

by Guangyu Wang, Guangyu Wang, Guangyu Wang, Ana Sofia Cruz, Ana Sofia Cruz, Keith Youker, Keith Youker, Hernan G. Marcos-Abdala, Hernan G. Marcos-Abdala, Rajarajan A. Thandavarayan, Rajarajan A. Thandavarayan, John P. Cooke, John P. Cooke, Guillermo Torre-Amione, Guillermo Torre-Amione, Guillermo Torre-Amione, Kaifu Chen, Kaifu Chen, Kaifu Chen, Arvind Bhimaraj, Arvind Bhimaraj
Published 2021-01-01

nAChRs mediate human embryonic stem cell-derived endothelial cells: proliferation, apoptosis, and angiogenesis.

by Jin Yu, Ngan F Huang, Kitchener D Wilson, Jeffrey B Velotta, Mei Huang, Zongjin Li, Andrew Lee, Robert C Robbins, John P Cooke, Joseph C Wu
Published 2009-09-01

Machine learning uncovers cell identity regulator by histone code

by Bo Xia, Dongyu Zhao, Guangyu Wang, Min Zhang, Jie Lv, Alin S. Tomoiaga, Yanqiang Li, Xin Wang, Shu Meng, John P. Cooke, Qi Cao, Lili Zhang, Kaifu Chen
Published 2020-06-01

FXR agonist INT-747 upregulates DDAH expression and enhances insulin sensitivity in high-salt fed Dahl rats.

by Yohannes T Ghebremariam, Keisuke Yamada, Jerry C Lee, Christine L C Johnson, Dorothee Atzler, Maike Anderssohn, Rani Agrawal, John P Higgins, Andrew J Patterson, Rainer H Böger, John P Cooke
Published 2013-01-01

Broad genic repression domains signify enhanced silencing of oncogenes

by Dongyu Zhao, Lili Zhang, Min Zhang, Bo Xia, Jie Lv, Xinlei Gao, Guangyu Wang, Qingshu Meng, Yang Yi, Sen Zhu, Alin S. Tomoiaga, Min Gyu Lee, John P. Cooke, Qi Cao, Kaifu Chen
Published 2020-11-01

Integration of induced pluripotent stem cell-derived endothelial cells with polycaprolactone/gelatin-based electrospun scaffolds for enhanced therapeutic angiogenesis

by Richard P. Tan, Alex H. P. Chan, Katarina Lennartsson, Maria M. Miravet, Bob S. L. Lee, Jelena Rnjak-Kovacina, Zoe E. Clayton, John P. Cooke, Martin K. C. Ng, Sanjay Patel, Steven G. Wise
Published 2018-03-01

Discovery of novel determinants of endothelial lineage using chimeric heterokaryons

by Wing Tak Wong, Gianfranco Matrone, XiaoYu Tian, Simion Alin Tomoiaga, Kin Fai Au, Shu Meng, Sayumi Yamazoe, Daniel Sieveking, Kaifu Chen, David M Burns, James K Chen, Helen M Blau, John P Cooke
Published 2017-03-01

Identification of Bone Marrow Cell Subpopulations Associated with Improved Functional Outcomes in Patients with Chronic Left Ventricular Dysfunction: An Embedded Cohort Evaluation...

by Doris A. Taylor, Emerson C. Perin, James T. Willerson, Claudia Zierold, Micheline Resende, Marjorie Carlson, Belinda Nestor, Elizabeth Wise, Aaron Orozco, Carl J. Pepine, Timothy D. Henry, Stephen G. Ellis, David X. M. Zhao, Jay H. Traverse, John P. Cooke, Robert C. Schutt, Aruni Bhatnagar, Maria B. Grant, Dejian Lai, Brian H. Johnstone, Shelly L. Sayre, Lem Moyé, Ray F. Ebert, Roberto Bolli, Robert D. Simari
Published 2016-09-01

Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phen...

by Sivareddy Kotla, Aijun Zhang, Masaki Imanishi, Kyung Ae Ko, Steven H. Lin, Young Jin Gi, Margie Moczygemba, Sevinj Isgandarova, Keri L. Schadler, Caroline Chung, Sarah A. Milgrom, Jose Banchs, Syed Wamique Yusuf, Diana N. Amaya, Huifang Guo, Tamlyn N. Thomas, Ying H. Shen, Anita Deswal, Joerg Herrmann, Eugenie S. Kleinerman, Mark L. Entman, John P. Cooke, Giovanni Schifitto, Sanjay B. Maggirwar, Elena McBeath, Anisha A. Gupte, Sunil Krishnan, Zarana S. Patel, Yisang Yoon, Jared K. Burks, Keigi Fujiwara, Paul S. Brookes, Nhat-Tu Le, Dale J. Hamilton, Jun-ichi Abe
Published 2021-11-01