Regioselective Synthesis of Novel N2- and N4-Substituted 7-Methylpyrazolo[4,5-e][1,2,4]thiadiazines

Regioselective Synthesis of Novel N2- and N4-Substituted 7-Methylpyrazolo[4,5-e][1,2,4]thiadiazines

The new compound 7-methylpyrazolo[4,5-e][1,2,4]thiadiazin-3(2H,4H)-one1,1-dioxide (5) was synthesized and its novel mono N2- or N4-substituted derivatives 6and 7 were prepared by regioselective N-alkylation of 5 with different molar ratios ofNaH and alkyl halides. Based on the regioselective alkylat...

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Bibliographic Details
Main Authors: Salvador Vega, Maria Teresa Molina, Wenfang Xu, Niangen Chen, Renzhang Yan, Xinyong Liu
Format: Article
Language:English
Published: MDPI AG 2006-11-01
Series:Molecules
Subjects:
Pyrazolothiadiazines
regioselectivity
synthesis
alkylation
one-pot reaction
Online Access:http://www.mdpi.com/1420-3049/11/11/827/

Internet

http://www.mdpi.com/1420-3049/11/11/827/

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