BrownieAligner: accurate alignment of Illumina sequencing data to de Bruijn graphs

Abstract Background Aligning short reads to a reference genome is an important task in many genome analysis pipelines. This task is computationally more complex when the reference genome is provided in the form of a de Bruijn graph instead of a linear sequence string. Results We present a branch and...

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Bibliographic Details
Main Authors: Mahdi Heydari, Giles Miclotte, Yves Van de Peer, Jan Fostier
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-018-2319-7