Positive Diagnosis of Ancient Leprosy and Tuberculosis Using Ancient DNA and Lipid Biomarkers

Positive Diagnosis of Ancient Leprosy and Tuberculosis Using Ancient DNA and Lipid Biomarkers

Diagnosis of leprosy and tuberculosis in archaeological material is most informative when based upon entire genomes. Ancient DNA (aDNA) is often degraded but amplification of specific fragments also provides reliable diagnoses. Cell wall lipid biomarkers can distinguish ancient leprosy from tubercul...

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Bibliographic Details
Main Authors: Helen D. Donoghue, G. Michael Taylor, Graham R. Stewart, Oona Y. -C. Lee, Houdini H. T. Wu, Gurdyal S. Besra, David E. Minnikin
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Diversity
Subjects:
aDNA
cell wall lipids
evolution
genotyping
Mycobacterium leprae
Mycobacterium tuberculosis
palaeopathology
Online Access:https://www.mdpi.com/1424-2818/9/4/46

Internet

https://www.mdpi.com/1424-2818/9/4/46

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