Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars

by Elizabeth Fullam, Ivan Prokes, Klaus Fütterer, Gurdyal S. Besra
Published 2016-01-01

Antibiotics and resistance: the two-sided coin of the mycobacterial cell wall

by Sarah M. Batt, Christopher E. Burke, Alice R. Moorey, Gurdyal S. Besra
Published 2020-12-01

Utilisation of the Prestwick Chemical Library to identify drugs that inhibit the growth of mycobacteria.

by Panchali Kanvatirth, Rose E Jeeves, Joanna Bacon, Gurdyal S Besra, Luke J Alderwick
Published 2019-01-01

Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthases.

by Alistair K Brown, Rebecca C Taylor, Apoorva Bhatt, Klaus Fütterer, Gurdyal S Besra
Published 2009-07-01

Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis.

by Veeraraghavan Usha, Judith V Hobrath, Sudagar S Gurcha, Robert C Reynolds, Gurdyal S Besra
Published 2012-01-01

Ppm1-encoded polyprenyl monophosphomannose synthase activity is essential for lipoglycan synthesis and survival in mycobacteria.

by Amrita K Rana, Albel Singh, Sudagar S Gurcha, Liam R Cox, Apoorva Bhatt, Gurdyal S Besra
Published 2012-01-01

AftD functions as an α1 → 5 arabinofuranosyltransferase involved in the biosynthesis of the mycobacterial cell wall core

by Luke J. Alderwick, Helen L. Birch, Karin Krumbach, Michael Bott, Lothar Eggeling, Gurdyal S. Besra
Published 2018-03-01

Biochemical and phenotypic characterisation of the Mycobacterium smegmatis transporter UspABC

by Magdalena Karlikowska, Albel Singh, Apoorva Bhatt, Sascha Ott, Andrew R. Bottrill, Gurdyal S. Besra, Elizabeth Fullam
Published 2021-12-01

Promotion or Suppression of Murine Intestinal Polyp Development by iNKT Cell Directed Immunotherapy

by Ying Wang, Saikiran K. Sedimbi, Linda Löfbom, Gurdyal S. Besra, Steven A. Porcelli, Susanna L. Cardell
Published 2019-03-01

Gram-positive bacterial lipoglycans based on a glycosylated diacylglycerol lipid anchor are microbe-associated molecular patterns recognized by TLR2.

by Landry Blanc, Romain Castanier, Arun K Mishra, Aurélie Ray, Gurdyal S Besra, Iain Sutcliffe, Alain Vercellone, Jérôme Nigou
Published 2013-01-01

The C-terminal domain of the Arabinosyltransferase Mycobacterium tuberculosis EmbC is a lectin-like carbohydrate binding module.

by Luke J Alderwick, Georgina S Lloyd, Hemza Ghadbane, John W May, Apoorva Bhatt, Lothar Eggeling, Klaus Fütterer, Gurdyal S Besra
Published 2011-02-01

The hydrolase LpqI primes mycobacterial peptidoglycan recycling

by Patrick J. Moynihan, Ian T. Cadby, Natacha Veerapen, Monika Jankute, Marialuisa Crosatti, Galina V. Mukamolova, Andrew L. Lovering, Gurdyal S. Besra
Published 2019-06-01

MKAN27435 is required for the biosynthesis of higher subclasses of lipooligosaccharides in Mycobacterium kansasii.

by Vijayashankar Nataraj, Poh-choo Pang, Stuart M Haslam, Natacha Veerapen, David E Minnikin, Anne Dell, Gurdyal S Besra, Apoorva Bhatt
Published 2015-01-01

Anti-tubercular derivatives of rhein require activation by the monoglyceride lipase Rv0183

by Katherine A. Abrahams, Wei Hu, Gang Li, Yu Lu, Emily J. Richardson, Nicholas J. Loman, Haihong Huang, Gurdyal S. Besra
Published 2020-12-01

Correction: Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells

by Rebeca Jimeno, Marta Lebrusant-Fernandez, Christian Margreitter, Beth Lucas, Natacha Veerapen, Gurdyal S Besra, Franca Fraternali, Jo Spencer, Graham Anderson, Patricia Barral
Published 2020-03-01

Positive Diagnosis of Ancient Leprosy and Tuberculosis Using Ancient DNA and Lipid Biomarkers

by Helen D. Donoghue, G. Michael Taylor, Graham R. Stewart, Oona Y. -C. Lee, Houdini H. T. Wu, Gurdyal S. Besra, David E. Minnikin
Published 2017-10-01

Thiacetazone, an antitubercular drug that inhibits cyclopropanation of cell wall mycolic acids in mycobacteria.

by Anuradha Alahari, Xavier Trivelli, Yann Guérardel, Lynn G Dover, Gurdyal S Besra, James C Sacchettini, Robert C Reynolds, Geoffrey D Coxon, Laurent Kremer
Published 2007-12-01

Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells

by Rebeca Jimeno, Marta Lebrusant-Fernandez, Christian Margreitter, Beth Lucas, Natacha Veerapen, Gavin Kelly, Gurdyal S Besra, Franca Fraternali, Jo Spencer, Graham Anderson, Patricia Barral
Published 2019-12-01

Generation of Liposomes to Study the Effect of <i>Mycobacterium Tuberculosis</i> Lipids on HIV-1 <i>cis</i>- and <i>trans</i>-Infections

by Marion Pouget, Anna K. Coussens, Alessandra Ruggiero, Anastasia Koch, Jordan Thomas, Gurdyal S. Besra, Robert J. Wilkinson, Apoorva Bhatt, Georgios Pollakis, William A. Paxton
Published 2021-02-01

Lcp1 Is a Phosphotransferase Responsible for Ligating Arabinogalactan to Peptidoglycan in Mycobacterium tuberculosis

by James Harrison, Georgina Lloyd, Maju Joe, Todd L. Lowary, Edward Reynolds, Hannah Walters-Morgan, Apoorva Bhatt, Andrew Lovering, Gurdyal S. Besra, Luke J. Alderwick
Published 2016-08-01