Toxin-Induced and Genetic Animal Models of Parkinson's Disease

Parkinson's disease (PD) is a common progressive neurodegenerative disorder. The major pathological hallmarks of PD are the selective loss of nigrostriatal dopaminergic neurons and the presence of intraneuronal aggregates termed Lewy bodies (LBs), but the pathophysiological mechanisms are not f...

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Bibliographic Details
Main Authors: Shin Hisahara, Shun Shimohama
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.4061/2011/951709