TGFβ1 regulates the inflammatory response during chronic neurodegeneration

The ME7 model of murine prion disease shows an atypical inflammatory response characterized by morphologically activated microglia and an anti-inflammatory cytokine profile with a marked expression of TGFβ1. The investigation of the role of TGFβ1 during a time course disease shows that its expressio...

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Bibliographic Details
Main Authors: Delphine Boche, Colm Cunningham, Fabian Docagne, Helen Scott, V. Hugh Perry
Format: Article
Language:English
Published: Elsevier 2006-06-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106000064