Grape Polyphenols Attenuate Diet-Induced Obesity and Hepatic Steatosis in Mice in Association With Reduced Butyrate and Increased Markers of Intestinal Carbohydrate Oxidation

Grape Polyphenols Attenuate Diet-Induced Obesity and Hepatic Steatosis in Mice in Association With Reduced Butyrate and Increased Markers of Intestinal Carbohydrate Oxidation

A Western Diet (WD) low in fiber but high in fats and sugars contributes to obesity and non-alcoholic fatty liver disease (NAFLD). Supplementation with grape polyphenols (GPs) rich in B-type proanthocyanidins (PACs) can attenuate symptoms of cardiometabolic disease and alter the gut microbiota and i...

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Bibliographic Details
Main Authors: Esther Mezhibovsky, Kim A. Knowles, Qiyue He, Ke Sui, Kevin M. Tveter, Rocio M. Duran, Diana E. Roopchand
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Nutrition
Subjects:
hepatic steatosis
energy expenditure
Akkermansia muciniphila
butyrate
intestinal metabolism
Western diet
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2021.675267/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2021.675267/full

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