S6K1 and 4E-BP1 are independent regulated and control cellular growth in bladder cancer.

Aberrant activation and mutation status of proteins in the phosphatidylinositol-3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) and the mitogen activated protein kinase (MAPK) signaling pathways have been linked to tumorigenesis in various tumors including urothelial carcinoma (UC). However...

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Bibliographic Details
Main Authors: Roman Nawroth, Florian Stellwagen, Wolfgang A Schulz, Robert Stoehr, Arndt Hartmann, Bernd J Krause, Juergen E Gschwend, Margitta Retz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3216974?pdf=render