Allele- and Tir-independent functions of intimin in diverse animal infection models

Allele- and Tir-independent functions of intimin in diverse animal infection models

Upon binding to intestinal epithelial cells, enterohemorrhagic E. coli (EHEC), enteropathogenic E. coli (EPEC), and Citrobacter rodentium trigger formation of actin pedestals beneath bound bacteria. Pedestal formation has been associated with enhanced colonization, and requires intimin, an adhesin t...

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Bibliographic Details
Main Authors: Emily M Mallick, Michael John Brady, Steven A Luperchio, Vijay eVanguri, Loranne eMagoun, Hui eLiu, Barbara J Sheppard, Jean eMukherjee, Arthur eDonohue-Rolfe, Saul eTzipori, John M Leong, David B Schauer
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-01-01
Series:Frontiers in Microbiology
Subjects:
Citrobacter rodentium
Enterohemorrhagic Escherichia coli
Enteropathogenic Escherichia coli
Intimin
invasin
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00011/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00011/full

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