Effect of human scavenger receptor class A overexpression in bone marrow-derived cells on lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knockout mice

Scavenger receptors, which include various classes, play an important role in atherogenesis by mediating the unrestricted uptake of modified lipoproteins, resulting in the massive accumulation of cholesteryl esters. Because macrophage-derived foam cells are considered to be an important feature in e...

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Bibliographic Details
Main Authors: Nicole Herijgers, Menno P.J. de Winther, Miranda Van Eck, Louis M. Havekes, Marten H. Hofker, Peter M. Hoogerbrugge, Theo J.C. Van Berkel
Format: Article
Language:English
Published: Elsevier 2000-09-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520334520