Kinetic Characterization of Novel HIV-1 Entry Inhibitors: Discovery of a Relationship between Off-Rate and Potency

Kinetic Characterization of Novel HIV-1 Entry Inhibitors: Discovery of a Relationship between Off-Rate and Potency

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The entry of HIV-1 into permissible cells remains an extremely attractive and underexploited<br />therapeutic intervention point [...]

Bibliographic Details
Main Authors: Megan E. Meuser, Michael B. Murphy, Adel A. Rashad, Simon Cocklin
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Proceedings
Subjects:
bioisosteres
HIV-1 Env
antiviral
surface plasmon resonance
computer-aided drug design
Online Access:https://www.mdpi.com/2504-3900/22/1/77

Internet

https://www.mdpi.com/2504-3900/22/1/77

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