Formation of Filamentous Tau Aggregations in Transgenic Mice Expressing V337M Human Tau

Formation of Filamentous Tau Aggregations in Transgenic Mice Expressing V337M Human Tau

Formation of neurofibrillary tangles (NFTs) is the most common feature in several neurodegenerative diseases, including Alzheimer's disease (AD). Here we report the formation of filamentous tau aggregations having a β-sheet structure in transgenic mice expressing mutant human tau. These mice co...

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Bibliographic Details
Main Authors: Kentaro Tanemura, Takumi Akagi, Miyuki Murayama, Naomi Kikuchi, Ohoshi Murayama, Tsutomu Hashikawa, Yuji Yoshiike, Jung-Mi Park, Keiko Matsuda, Shinobu Nakao, Xiaoyan Sun, Shinji Sato, Haruyasu Yamaguchi, Akihiko Takashima
Format: Article
Language:English
Published: Elsevier 2001-12-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996101904395

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http://www.sciencedirect.com/science/article/pii/S0969996101904395

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