Deficient spermiogenesis in mice lacking Rlim

Deficient spermiogenesis in mice lacking Rlim

The X-linked gene Rlim plays major roles in female mouse development and reproduction, where it is crucial for the maintenance of imprinted X chromosome inactivation in extraembryonic tissues of embryos. However, while females carrying a systemic Rlim knockout (KO) die around implantation, male Rlim...

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Bibliographic Details
Main Authors: Feng Wang, Maria Gracia Gervasi, Ana Bošković, Fengyun Sun, Vera D Rinaldi, Jun Yu, Mary C Wallingford, Darya A Tourzani, Jesse Mager, Lihua Julie Zhu, Oliver J Rando, Pablo E Visconti, Lara Strittmatter, Ingolf Bach
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-02-01
Series:eLife
Subjects:
Rlim
spermiogenesis
cytoplasmic reduction
mouse genetics
Online Access:https://elifesciences.org/articles/63556

Internet

https://elifesciences.org/articles/63556

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