A clinical evaluation of statin pleiotropy: statins selectively and dose-dependently reduce vascular inflammation.

Statins are thought to reduce vascular inflammation through lipid independent mechanisms. Evaluation of such an effect in atherosclerotic disease is complicated by simultaneous effects on lipid metabolism. Abdominal aortic aneurysms (AAA) are part of the atherosclerotic spectrum of diseases. Unlike...

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Bibliographic Details
Main Authors: Evelien van der Meij, Giel G Koning, Patrick W Vriens, Marcel F Peeters, C Arnoud Meijer, Kim E Kortekaas, Ronald L Dalman, J Hajo van Bockel, Roeland Hanemaaijer, Teake Kooistra, Robert Kleemann, Jan H N Lindeman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3551939?pdf=render