Flavonoid 4′-O-Methylkuwanon E from Morus alba Induces the Differentiation of THP-1 Human Leukemia Cells

Aims. In this work we studied cytodifferentiation effects of newly characterized prenyl flavonoid 4′-O-methylkuwanon E (4ME) isolated from white mulberry (Morus alba L.). Main Methods. Cell growth and viability were measured by dye exclusion assay; cell cycle and surface antigen CD11b were monitored...

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Main Authors: Peter Kollar, Tomáš Bárta, Stanislava Keltošová, Pavlína Trnová, Veronika Müller Závalová, Karel Šmejkal, Jan Hošek, Radek Fedr, Karel Souček, Aleš Hampl
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2015/251895