Characterizing the Key Metabolic Pathways of the Neonatal Mouse Heart Using a Quantitative Combinatorial Omics Approach

Characterizing the Key Metabolic Pathways of the Neonatal Mouse Heart Using a Quantitative Combinatorial Omics Approach

The heart of a newborn mouse has an exceptional capacity to regenerate from myocardial injury that is lost within the first week of its life. In order to elucidate the molecular mechanisms taking place in the mouse heart during this critical period we applied an untargeted combinatory multiomics app...

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Bibliographic Details
Main Authors: Maciej M. Lalowski, Susann Björk, Piet Finckenberg, Rabah Soliymani, Miikka Tarkia, Giulio Calza, Daria Blokhina, Sari Tulokas, Matti Kankainen, Päivi Lakkisto, Marc Baumann, Esko Kankuri, Eero Mervaala
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Physiology
Subjects:
neonatal heart
omics
fructolysis
hypoxia
cardiomyocyte proliferation
regeneration
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00365/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2018.00365/full

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