Cardiovascular disease risk factors induce mesenchymal features and senescence in mouse cardiac endothelial cells

by Karthik Amudhala Hemanthakumar, Shentong Fang, Andrey Anisimov, Mikko I Mäyränpää, Eero Mervaala, Riikka Kivelä
Published 2021-03-01

Discovery of Small Molecules that Activate RNA Methylation through Cooperative Binding to the METTL3-14-WTAP Complex Active Site

by Simona Selberg, Daria Blokhina, Maria Aatonen, Pertti Koivisto, Antti Siltanen, Eero Mervaala, Esko Kankuri, Mati Karelson
Published 2019-03-01

Evaluation of Optogenetic Electrophysiology Tools in Human Stem Cell-Derived Cardiomyocytes

by Susann Björk, Elina A. Ojala, Tommy Nordström, Antti Ahola, Mikko Liljeström, Jari Hyttinen, Esko Kankuri, Eero Mervaala
Published 2017-11-01

Milk Products Containing Bioactive Tripeptides Have an Antihypertensive Effect in Double Transgenic Rats (dTGR) Harbouring Human Renin and Human Angiotensinogen Genes

by Tiina Jauhiainen, Taru Pilvi, Zhong Jian Cheng, Hannu Kautiainen, Dominik N. Müller, Heikki Vapaatalo, Riitta Korpela, Eero Mervaala
Published 2010-01-01

Comparison of arrhythmogenicity and proinflammatory activity induced by intramyocardial or epicardial myoblast sheet delivery in a rat model of ischemic heart failure.

by Tommi Pätilä, Shigeru Miyagawa, Yukiko Imanishi, Satsuki Fukushima, Antti Siltanen, Eero Mervaala, Esko Kankuri, Ari Harjula, Yoshiki Sawa
Published 2015-01-01

Activation of protective and damaging components of the cardiac renin-angiotensin system after myocardial infarction in experimental diabetes

by Tom Bäcklund, Päivi Lakkisto, Eeva Palojoki, Tina Grönholm, Antti Saraste, Piet Finckenberg, Eero Mervaala, Ilkka Tikkanen, Mika Laine
Published 2007-06-01

Distinct Effects of Calorie Restriction and Resveratrol on Diet-Induced Obesity and Fatty Liver Formation

by Eveliina Tauriainen, Mira Luostarinen, Essi Martonen, Piet Finckenberg, Miia Kovalainen, Anne Huotari, Karl-Heinz Herzig, Anne Lecklin, Eero Mervaala
Published 2011-01-01

HiPS-Endothelial Cells Acquire Cardiac Endothelial Phenotype in Co-culture With hiPS-Cardiomyocytes

by Emmi Helle, Emmi Helle, Minna Ampuja, Alexandra Dainis, Laura Antola, Elina Temmes, Elina Temmes, Erik Tolvanen, Eero Mervaala, Riikka Kivelä, Riikka Kivelä
Published 2021-08-01

Extracellular membrane vesicles from umbilical cord blood-derived MSC protect against ischemic acute kidney injury, a feature that is lost after inflammatory conditioning

by Lotta Kilpinen, Ulla Impola, Lotta Sankkila, Ilja Ritamo, Maria Aatonen, Sami Kilpinen, Jarno Tuimala, Leena Valmu, Jouko Levijoki, Piet Finckenberg, Pia Siljander, Esko Kankuri, Eero Mervaala, Saara Laitinen
Published 2013-12-01

Characterizing the Key Metabolic Pathways of the Neonatal Mouse Heart Using a Quantitative Combinatorial Omics Approach

by Maciej M. Lalowski, Susann Björk, Piet Finckenberg, Rabah Soliymani, Miikka Tarkia, Giulio Calza, Daria Blokhina, Sari Tulokas, Matti Kankainen, Matti Kankainen, Päivi Lakkisto, Marc Baumann, Esko Kankuri, Eero Mervaala
Published 2018-04-01

Alternative oxidase‐mediated respiration prevents lethal mitochondrial cardiomyopathy

by Jayasimman Rajendran, Janne Purhonen, Saara Tegelberg, Olli‐Pekka Smolander, Matthias Mörgelin, Jan Rozman, Valerie Gailus‐Durner, Helmut Fuchs, Martin Hrabe de Angelis, Petri Auvinen, Eero Mervaala, Howard T Jacobs, Marten Szibor, Vineta Fellman, Jukka Kallijärvi
Published 2019-01-01

VEGF‐B‐induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart

by Riikka Kivelä, Maija Bry, Marius R Robciuc, Markus Räsänen, Miia Taavitsainen, Johanna MU Silvola, Antti Saraste, Juha J Hulmi, Andrey Anisimov, Mikko I Mäyränpää, Jan H Lindeman, Lauri Eklund, Sanna Hellberg, Ruslan Hlushchuk, Zhen W Zhuang, Michael Simons, Valentin Djonov, Juhani Knuuti, Eero Mervaala, Kari Alitalo
Published 2014-03-01

Epitranscriptomics of Ischemic Heart Disease—The IHD-EPITRAN Study Design and Objectives

by Vilbert Sikorski, Pasi Karjalainen, Daria Blokhina, Kati Oksaharju, Jahangir Khan, Shintaro Katayama, Helena Rajala, Satu Suihko, Suvi Tuohinen, Kari Teittinen, Annu Nummi, Antti Nykänen, Arda Eskin, Christoffer Stark, Fausto Biancari, Jan Kiss, Jarmo Simpanen, Jussi Ropponen, Karl Lemström, Kimmo Savinainen, Maciej Lalowski, Markku Kaarne, Mikko Jormalainen, Outi Elomaa, Pertti Koivisto, Peter Raivio, Pia Bäckström, Sebastian Dahlbacka, Simo Syrjälä, Tiina Vainikka, Tommi Vähäsilta, Nurcan Tuncbag, Mati Karelson, Eero Mervaala, Tatu Juvonen, Mika Laine, Jari Laurikka, Antti Vento, Esko Kankuri
Published 2021-06-01