The Role of Streptococcal and Staphylococcal Exotoxins and Proteases in Human Necrotizing Soft Tissue Infections

The Role of Streptococcal and Staphylococcal Exotoxins and Proteases in Human Necrotizing Soft Tissue Infections

Necrotizing soft tissue infections (NSTIs) are critical clinical conditions characterized by extensive necrosis of any layer of the soft tissue and systemic toxicity. Group A streptococci (GAS) and <i>Staphylococcus aureus</i> are two major pathogens associated with monomicrobial NSTIs....

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Bibliographic Details
Main Authors: Patience Shumba, Srikanth Mairpady Shambat, Nikolai Siemens
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Toxins
Subjects:
<i>Streptococcus pyogenes</i>
group A streptococcus
<i>Staphylococcus aureus</i>
skin infections
necrotizing soft tissue infections
pore-forming toxins
superantigens
immunomodulatory proteases
immune responses
Online Access:https://www.mdpi.com/2072-6651/11/6/332

Internet

https://www.mdpi.com/2072-6651/11/6/332

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