Systemic inflammation switches the inflammatory cytokine profile in CNS Wallerian degeneration

Axon loss in the CNS is characteristic of many neurodegenerative diseases but the mechanisms of axon degeneration are poorly understood. In particular, we know little of the inflammatory response triggered by CNS axon degeneration with comparison to that provoked by death of the neuronal cell body....

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Bibliographic Details
Main Authors: Karine Palin, Colm Cunningham, Penny Forse, V. Hugh Perry, Nick Platt
Format: Article
Language:English
Published: Elsevier 2008-04-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107002677